Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia–lymphoma cells

Adult T-cell leukemia–lymphoma (ATL), an aggressive neoplasm etiologically associated with HTLV-1, is a chemoresistant malignancy. Heat shock protein 90 (HSP90) is involved in folding and functions as a chaperone for multiple client proteins, many of which are important in tumorigenesis. In this stu...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Taniguchi, Hiroaki, Hasegawa, Hiroo, Sasaki, Daisuke, Ando, Koji, Sawayama, Yasushi, Imanishi, Daisuke, Taguchi, Jun, Imaizumi, Yoshitaka, Hata, Tomoko, Tsukasaki, Kunihiro, Uno, Naoki, Morinaga, Yoshitomo, Yanagihara, Katsunori, Miyazaki, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317953/
https://ncbi.nlm.nih.gov/pubmed/25263741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12540
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