IDH2 and TP53 mutations are correlated with gliomagenesis in a patient with Maffucci syndrome

We report on a 24-year-old woman who was diagnosed as having Maffucci syndrome with anaplastic astrocytoma. We analyzed the IDH1 and IDH2 mutations of enchondroma, hemangioma and anaplastic astrocytoma tissues and the same somatic mosaic mutation in IDH2 gene was identified in all these tissues. In...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Moriya, Kunihiko, Kaneko, Mika K, Liu, Xing, Hosaka, Masami, Fujishima, Fumiyoshi, Sakuma, Jun, Ogasawara, Satoshi, Watanabe, Mika, Sasahara, Yoji, Kure, Shigeo, Kato, Yukinari
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317937/
https://ncbi.nlm.nih.gov/pubmed/24344754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12337
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