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IDH2 and TP53 mutations are correlated with gliomagenesis in a patient with Maffucci syndrome
We report on a 24-year-old woman who was diagnosed as having Maffucci syndrome with anaplastic astrocytoma. We analyzed the IDH1 and IDH2 mutations of enchondroma, hemangioma and anaplastic astrocytoma tissues and the same somatic mosaic mutation in IDH2 gene was identified in all these tissues. In...
שמור ב:
| הוצא לאור ב: | Cancer Sci |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BlackWell Publishing Ltd
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317937/ https://ncbi.nlm.nih.gov/pubmed/24344754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12337 |
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