IDH2 and TP53 mutations are correlated with gliomagenesis in a patient with Maffucci syndrome

We report on a 24-year-old woman who was diagnosed as having Maffucci syndrome with anaplastic astrocytoma. We analyzed the IDH1 and IDH2 mutations of enchondroma, hemangioma and anaplastic astrocytoma tissues and the same somatic mosaic mutation in IDH2 gene was identified in all these tissues. In...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Moriya, Kunihiko, Kaneko, Mika K, Liu, Xing, Hosaka, Masami, Fujishima, Fumiyoshi, Sakuma, Jun, Ogasawara, Satoshi, Watanabe, Mika, Sasahara, Yoji, Kure, Shigeo, Kato, Yukinari
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317937/
https://ncbi.nlm.nih.gov/pubmed/24344754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12337
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