IDH1/IDH2 but Not TP53 Mutations Predict Prognosis in Bulgarian Glioblastoma Patients

Mutations in genes encoding isocitrate dehydrogenase isoforms 1 (IDH1) and 2 (IDH2) have been associated with good prognosis for patients with brain neoplasias and have been commonly found together with mutated TP53 gene. To determine the prevalence of IDH1, IDH2, and TP53 mutations and their impact...

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Detalhes bibliográficos
Main Authors: Stancheva, Gergana, Goranova, Teodora, Laleva, Maria, Kamenova, Margarita, Mitkova, Atanaska, Velinov, Nikolay, Poptodorov, George, Mitev, Vanio, Kaneva, Radka, Gabrovsky, Nikolay
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017788/
https://ncbi.nlm.nih.gov/pubmed/24868540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/654727
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