IDH1/IDH2 but Not TP53 Mutations Predict Prognosis in Bulgarian Glioblastoma Patients

Mutations in genes encoding isocitrate dehydrogenase isoforms 1 (IDH1) and 2 (IDH2) have been associated with good prognosis for patients with brain neoplasias and have been commonly found together with mutated TP53 gene. To determine the prevalence of IDH1, IDH2, and TP53 mutations and their impact...

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Библиографические подробности
Главные авторы: Stancheva, Gergana, Goranova, Teodora, Laleva, Maria, Kamenova, Margarita, Mitkova, Atanaska, Velinov, Nikolay, Poptodorov, George, Mitev, Vanio, Kaneva, Radka, Gabrovsky, Nikolay
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017788/
https://ncbi.nlm.nih.gov/pubmed/24868540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/654727
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