Antitumor effect of fibrin glue containing temozolomide against malignant glioma

Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells. We investigated fibrin glue (FG) as a drug delivery system for the local administration of high-concentration TMZ aimed at preventing glioma recurrence. Our high-power li...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Anai, Shigeo, Hide, Takuichiro, Takezaki, Tatsuya, Kuroda, Jun-ichiro, Shinojima, Naoki, Makino, Keishi, Nakamura, Hideo, Yano, Shigetoshi, Kuratsu, Jun-ichi
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317836/
https://ncbi.nlm.nih.gov/pubmed/24673719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12397
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