Antitumor effect of fibrin glue containing temozolomide against malignant glioma

Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells. We investigated fibrin glue (FG) as a drug delivery system for the local administration of high-concentration TMZ aimed at preventing glioma recurrence. Our high-power li...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Anai, Shigeo, Hide, Takuichiro, Takezaki, Tatsuya, Kuroda, Jun-ichiro, Shinojima, Naoki, Makino, Keishi, Nakamura, Hideo, Yano, Shigetoshi, Kuratsu, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317836/
https://ncbi.nlm.nih.gov/pubmed/24673719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12397
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