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Japanese phase I study of GC33, a humanized antibody against glypican-3 for advanced hepatocellular carcinoma

GC33 is a humanized mAb against human glypican-3 (GPC3). In the first-in-human study carried out in the USA, GC33 was well tolerated and showed preliminary antitumor activity in patients with advanced hepatocellular carcinoma. This study aimed to assess the safety, tolerability, and pharmacokinetic...

詳細記述

保存先:
書誌詳細
出版年:Cancer Sci
主要な著者: Ikeda, Masafumi, Ohkawa, Shinichi, Okusaka, Takuji, Mitsunaga, Shuichi, Kobayashi, Satoshi, Morizane, Chigusa, Suzuki, Ikue, Yamamoto, Shunsuke, Furuse, Junji
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317809/
https://ncbi.nlm.nih.gov/pubmed/24521523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12368
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