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Japanese phase I study of GC33, a humanized antibody against glypican-3 for advanced hepatocellular carcinoma
GC33 is a humanized mAb against human glypican-3 (GPC3). In the first-in-human study carried out in the USA, GC33 was well tolerated and showed preliminary antitumor activity in patients with advanced hepatocellular carcinoma. This study aimed to assess the safety, tolerability, and pharmacokinetic...
Gespeichert in:
| Veröffentlicht in: | Cancer Sci |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317809/ https://ncbi.nlm.nih.gov/pubmed/24521523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12368 |
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