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Alternative aspirins as antisickling agents: acetyl-3,5-dibromosalicylic acid.

Acetyl-3,5-dibromosalicylic acid (dibromoaspirin) is shown to be a potent acylating agent of intracellular hemoglobin in vitro. Transfer of the actyl group of dibromoaspirin to amino groups of hemoglobins A and S seems to occur predominantly at just two or three sites on these proteins. This acetyla...

詳細記述

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書誌詳細
主要な著者: Walder, J A, Zaugg, R H, Iwaoka, R S, Watkin, W G, Klotz, I M
フォーマット: Artigo
言語:Inglês
出版事項: 1977
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC431780/
https://ncbi.nlm.nih.gov/pubmed/271972
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