The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses

PA-X is a novel protein encoded by PA mRNA and is found to decrease the pathogenicity of pandemic 1918 H1N1 virus in mice. However, the importance of PA-X proteins in current epidemiologically important influenza A virus strains is not known. In this study, we report on the pathogenicity and patholo...

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Publicado no:Sci Rep
Main Authors: Gao, Huijie, Sun, Yipeng, Hu, Jiao, Qi, Lu, Wang, Jinliang, Xiong, Xin, Wang, Yu, He, Qiming, Lin, Yang, Kong, Weili, Seng, Lai-Giea, Sun, Honglei, Pu, Juan, Chang, Kin-Chow, Liu, Xiufan, Liu, Jinhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317690/
https://ncbi.nlm.nih.gov/pubmed/25652161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08262
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