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Mitotic Accumulation of Dimethylated Lysine 79 of Histone H3 Is Important for Maintaining Genome Integrity During Mitosis in Human Cells

The loss of genome stability is an early event that drives the development and progression of virtually all tumor types. Recent studies have revealed that certain histone post-translational modifications exhibit dynamic and global increases in abundance that coincide with mitosis and exhibit essenti...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Guppy, Brent J., McManus, Kirk J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317652/
https://ncbi.nlm.nih.gov/pubmed/25533199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.172874
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