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Intracranial Biodegradable Silica-Based Nimodipine Drug Release Implant for Treating Vasospasm in Subarachnoid Hemorrhage in an Experimental Healthy Pig and Dog Model

Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage. When administrated orally or intravenously, systemic hypotension is an undesirable side effect. Intracranial subarachnoid delivery of nimodipine during aneurysm clipping may be more eff...

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Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Koskimäki, Janne, Tarkia, Miikka, Ahtola-Sätilä, Tuula, Saloranta, Lasse, Simola, Outi, Forsback, Ari-Pekka, Laakso, Aki, Frantzén, Janek
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317635/
https://ncbi.nlm.nih.gov/pubmed/25685803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/715752
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