Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding P(II)-like Signal Transduction Protein DarA

The cyclic dimeric AMP nucleotide c-di-AMP is an essential second messenger in Bacillus subtilis. We have identified the protein DarA as one of the prominent c-di-AMP receptors in B. subtilis. Crystal structure analysis shows that DarA is highly homologous to P(II) signal transducer proteins. In con...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gundlach, Jan, Dickmanns, Achim, Schröder-Tittmann, Kathrin, Neumann, Piotr, Kaesler, Jan, Kampf, Jan, Herzberg, Christina, Hammer, Elke, Schwede, Frank, Kaever, Volkhard, Tittmann, Kai, Stülke, Jörg, Ficner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317042/
https://ncbi.nlm.nih.gov/pubmed/25433025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619619
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