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Intracisternal administration of an interleukin-6 receptor antagonist attenuates surgery-induced cognitive impairment by inhibition of neuroinflammatory responses in aged rats

Postoperative cognitive dysfunction (POCD) is common in elderly patients, and may persist or even evolve into Alzheimer’s disease. It has been hypothesized that POCD is mediated by surgery-induced inflammatory processes. As a pro-inflammatory cytokine, the detailed role of interleukin (IL)-6 in POCD...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Ther Med
Päätekijät: JIANG, PENG, LING, QIONG, LIU, HONGBO, TU, WEIFENG
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316944/
https://ncbi.nlm.nih.gov/pubmed/25667664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.2149
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