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Intracisternal administration of an interleukin-6 receptor antagonist attenuates surgery-induced cognitive impairment by inhibition of neuroinflammatory responses in aged rats

Postoperative cognitive dysfunction (POCD) is common in elderly patients, and may persist or even evolve into Alzheimer’s disease. It has been hypothesized that POCD is mediated by surgery-induced inflammatory processes. As a pro-inflammatory cytokine, the detailed role of interleukin (IL)-6 in POCD...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Ther Med
Main Authors: JIANG, PENG, LING, QIONG, LIU, HONGBO, TU, WEIFENG
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316944/
https://ncbi.nlm.nih.gov/pubmed/25667664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.2149
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