Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

BACKGROUND: Endoplasmic reticulum (ER) lumenal protein thiol redox balance resists dramatic variation in unfolded protein load imposed by diverse physiological challenges including compromise in the key upstream oxidases. Lumenal calcium depletion, incurred during normal cell signaling, stands out a...

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Udgivet i:BMC Biol
Main Authors: Avezov, Edward, Konno, Tasuku, Zyryanova, Alisa, Chen, Weiyue, Laine, Romain, Crespillo-Casado, Ana, Melo, Eduardo Pinho, Ushioda, Ryo, Nagata, Kazuhiro, Kaminski, Clemens F, Harding, Heather P, Ron, David
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316587/
https://ncbi.nlm.nih.gov/pubmed/25575667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0112-2
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