Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

BACKGROUND: Endoplasmic reticulum (ER) lumenal protein thiol redox balance resists dramatic variation in unfolded protein load imposed by diverse physiological challenges including compromise in the key upstream oxidases. Lumenal calcium depletion, incurred during normal cell signaling, stands out a...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Avezov, Edward, Konno, Tasuku, Zyryanova, Alisa, Chen, Weiyue, Laine, Romain, Crespillo-Casado, Ana, Melo, Eduardo Pinho, Ushioda, Ryo, Nagata, Kazuhiro, Kaminski, Clemens F, Harding, Heather P, Ron, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316587/
https://ncbi.nlm.nih.gov/pubmed/25575667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0112-2
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