Trimethylpsoralen induces small deletion mutations in Caenorhabditis elegans.

To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc-22 and pal-1 genes following TMP mutagenesis and analyzed them for restriction fragment length polymorphisms by Southern blot. Eleven of 21 unc-22 mutations exhibited restr...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Yandell, M D, Edgar, L G, Wood, W B
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7906415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1381
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