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Trimethylpsoralen induces small deletion mutations in Caenorhabditis elegans.

To examine the mutagenic spectrum of 4,5',8-trimethylpsoralen (TMP) in Caenorhabditis elegans, we isolated mutations in the unc-22 and pal-1 genes following TMP mutagenesis and analyzed them for restriction fragment length polymorphisms by Southern blot. Eleven of 21 unc-22 mutations exhibited...

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Autori principali: Yandell, M D, Edgar, L G, Wood, W B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC43162/
https://ncbi.nlm.nih.gov/pubmed/7906415
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