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Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines
AIM: To investigate the effect of interleukin (IL)-22 on hepatic fibrosis in mice and the possible mechanism involved. METHODS: Liver fibrosis was induced in male BALB/c mice by CCl(4). Recombinant IL-22 (rmIL-22) was administered intraperitoneally in CCl(4)-treated mice. Fibrosis was assessed by hi...
Shranjeno v:
| izdano v: | World J Gastroenterol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Baishideng Publishing Group Inc
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4316095/ https://ncbi.nlm.nih.gov/pubmed/25663772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i5.1531 |
| Oznake: |
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