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Differential Impact of Adenosine Nucleotides Released by Osteocytes on Breast Cancer Growth and Bone Metastasis

Extracellular ATP has been shown to either inhibit or promote cancer growth and migration; however the mechanism underlying this discrepancy remained elusive. Here, we demonstrate the divergent roles of ATP and adenosine released by bone osteocytes in breast cancers. We showed that conditioned media...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Zhou, Jade Z., Riquelme, Manuel A., Gao, Xiaoli, Ellies, Lesley G., Sun, Lu-Zhe, Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315766/
https://ncbi.nlm.nih.gov/pubmed/24837364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.113
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