The Role of Abcb5 Alleles in Susceptibility to Haloperidol-Induced Toxicity in Mice and Humans

BACKGROUND: We know very little about the genetic factors affecting susceptibility to drug-induced central nervous system (CNS) toxicities, and this has limited our ability to optimally utilize existing drugs or to develop new drugs for CNS disorders. For example, haloperidol is a potent dopamine an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Zheng, Ming, Zhang, Haili, Dill, David L., Clark, J. David, Tu, Susan, Yablonovitch, Arielle L., Tan, Meng How, Zhang, Rui, Rujescu, Dan, Wu, Manhong, Tessarollo, Lino, Vieira, Wilfred, Gottesman, Michael M., Deng, Suhua, Eberlin, Livia S., Zare, Richard N., Billard, Jean-Martin, Gillet, Jean-Pierre, Li, Jin Billy, Peltz, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315575/
https://ncbi.nlm.nih.gov/pubmed/25647612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001782
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados