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An Efficient Strategy for Heterologous Expression and Purification of Active Peptide Hainantoxin-IV
Hainantoxin-IV (HNTX-IV) from the venom of the spider Selenocosmia hainana is a potent antagonist that specifically inhibits the tetrodotoxin-sensitive (TTX-S) sodium channels. The toxin peptide consists of 35 amino acids and adopts a typical inhibitory cystine knot (ICK) motif. To obtain adequate H...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315428/ https://ncbi.nlm.nih.gov/pubmed/25647561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117099 |
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