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Conformational alteration of protein synthesis elongation factor EF-Tu by EF-Ts and by kirromycin.

Alterations of the structure of EF-Tu have been investigated by using the rate of EF-Tu cleavage by trypsin as a conformational probe. The presence of EF-Ts bound to EF-Tu results in a 10-fold increase in the cleavage rate. The antibiotic kirromycin, which inhibits protein synthesis by virtue of its...

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Detalhes bibliográficos
Main Authors: Blumenthal, T, Douglass, J, Smith, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431524/
https://ncbi.nlm.nih.gov/pubmed/269389
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