Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury

Infection of mice with human or murine adapted influenza A viruses results in a severe pneumonia. However, the results of studies from different laboratories show surprising variability, even in genetically similar strains. Differences in inoculum size related to the route of viral delivery (intrana...

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Veröffentlicht in:J Virol Methods
Hauptverfasser: Morales-Nebreda, Luisa, Chi, Monica, Lecuona, Emilia, Chandel, Navdeep S., Dada, Laura A., Ridge, Karen, Soberanes, Saul, Nigdelioglu, Recep, Sznajder, Jacob I., Mutlu, Gökhan M., Budinger, G.R. Scott, Radigan, Kathryn A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315182/
https://ncbi.nlm.nih.gov/pubmed/25239366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2014.09.004
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