Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.
Novobiocin and coumermycin are known to inhibit the replication of DNA iing of DNA catalyzed by E. coli DNA gyrase, a recently discovered enzyme that introduces negative superhelical turns into covalently circular DNA. The activity of DNA gyrase purified from a coumermycin-resistant mutant strain is...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
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| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
1976
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431506/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/794878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.12.4474 |
| الوسوم: |
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