Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase.

Choleragen and the isolated A protomer catalyzed the hydrolysis of NAD to ADP-ribose and nicotinamide. The protein with NADase activity (NAD nucleosidase; NAD glycohydrolase, EC 3-2-2-5) migrated on polyacrylamide gels with choleragen, and chromatographed on Bio-Gel P-60 columns with the A protomer....

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Bibliographic Details
Main Authors: Moss, J, Manganiello, V C, Vaughan, M
Format: Artigo
Language:Inglês
Published: 1976
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC431483/
https://ncbi.nlm.nih.gov/pubmed/188038
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