Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase.

Choleragen and the isolated A protomer catalyzed the hydrolysis of NAD to ADP-ribose and nicotinamide. The protein with NADase activity (NAD nucleosidase; NAD glycohydrolase, EC 3-2-2-5) migrated on polyacrylamide gels with choleragen, and chromatographed on Bio-Gel P-60 columns with the A protomer....

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Moss, J, Manganiello, V C, Vaughan, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1976
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/188038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.12.4424
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