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Fucoidan promotes osteoblast differentiation via JNK- and ERK-dependent BMP2–Smad 1/5/8 signaling in human mesenchymal stem cells

Fucoidan has attracted attention as a potential drug because of its biological activities, which include osteogenesis. However, the molecular mechanisms involved in the osteogenic activity of fucoidan in human alveolar bone marrow-derived mesenchymal stem cells (hABM-MSCs) remain largely unknown. We...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Mol Med
Main Authors: Kim, Beom Su, Kang, Hyo-Jin, Park, Ji-Yun, Lee, Jun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314586/
https://ncbi.nlm.nih.gov/pubmed/25572360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.95
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