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Regulation of protein synthesis in rabbit reticulocyte lysates: purification and initial characterization of the cyclic 3':5'-AMP independent protein kinase of the heme-regulated translational inhibitor.

The heme-regulated translational inhibitor (HRI) has been purified 4800-fold. On electrophoresis in sodium dodecyl sulfate/polyacrylamide gel, the purified HRI showed one major polypeptide band. The purified HRI inhibits protein synthesis in lysates containing optimal levels of hemin with inhibition...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ranu, R S, London, I M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1976
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1069987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.12.4349
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