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Direct Cytosolic Delivery of siRNA Using Nanoparticle-Stabilized Nanocapsules ()

We report the use of nanoparticle-stabilized nanocapsules (NPSC) for the direct cytosolic delivery of siRNA. In this approach, siRNA is complexed with cationic arginine-functionalized gold nanoparticles via electrostatic interactions, with the resulting ensemble self-assembled onto the surface of fa...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Autores principales: Jiang, Ying, Tang, Rui, Duncan, Bradley, Jiang, Ziwen, Yan, Bo, Mout, Rubul, Rotello, Vincent M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314441/
https://ncbi.nlm.nih.gov/pubmed/25393227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201409161
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