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Nanocapsule-mediated cytosolic siRNA delivery for anti-inflammatory treatment

The use of nanoparticle-stabilized nanocapsules for cytosolic siRNA delivery for immunomodulation in vitro and in vivo is reported. These NPSCs deliver siRNA directly to the cytosol of macrophages in vitro with concomitant knockdown of gene expression. In vivo studies showed directed delivery of NPS...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Jiang, Ying, Hardie, Joseph, Liu, Yuanchang, Ray, Moumita, Luo, Xiang, Das, Riddha, Landis, Ryan F., Farkas, Michelle, Rotello, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054481/
https://ncbi.nlm.nih.gov/pubmed/29883695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.06.001
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