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Nanocapsule-mediated cytosolic siRNA delivery for anti-inflammatory treatment
The use of nanoparticle-stabilized nanocapsules for cytosolic siRNA delivery for immunomodulation in vitro and in vivo is reported. These NPSCs deliver siRNA directly to the cytosol of macrophages in vitro with concomitant knockdown of gene expression. In vivo studies showed directed delivery of NPS...
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| Veröffentlicht in: | J Control Release |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054481/ https://ncbi.nlm.nih.gov/pubmed/29883695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.06.001 |
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