Loading...
Structural Basis for Cooperative Binding of Azoles to CYP2E1 as Interpreted through Guided Molecular Dynamics Simulations
CYP2E1 metabolizes a wide array of small, hydrophobic molecules, resulting in their detoxification or activation into carcinogens through Michaelis-Menten as well as cooperative mechanisms. Nevertheless, the molecular determinants for CYP2E1 specificity and metabolic efficiency toward these compound...
Na minha lista:
| Udgivet i: | J Mol Graph Model |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4314338/ https://ncbi.nlm.nih.gov/pubmed/25544389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2014.11.013 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|