Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)

Disruptions in GABAergic neurotransmission have been implicated in numerous CNS disorders, including epilepsy and neuropathic pain. Selective inhibition of neuronal and glial GABA transporter subtypes may offer unique therapeutic options for regaining balance between inhibitory and excitatory system...

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Vydáno v:Epilepsy Res
Hlavní autoři: Smith, Misty D., Saunders, Gerald W., Clausen, Rasmus P., Frǿlund, Bente, Krogsgaard-Larsen, Povl, Larsson, Orla M., Schousboe, Arne, Wilcox, Karen S., White, H. Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314296/
https://ncbi.nlm.nih.gov/pubmed/18262393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2007.12.009
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