Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)

Disruptions in GABAergic neurotransmission have been implicated in numerous CNS disorders, including epilepsy and neuropathic pain. Selective inhibition of neuronal and glial GABA transporter subtypes may offer unique therapeutic options for regaining balance between inhibitory and excitatory system...

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Detalhes bibliográficos
Publicado no:Epilepsy Res
Main Authors: Smith, Misty D., Saunders, Gerald W., Clausen, Rasmus P., Frǿlund, Bente, Krogsgaard-Larsen, Povl, Larsson, Orla M., Schousboe, Arne, Wilcox, Karen S., White, H. Steve
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314296/
https://ncbi.nlm.nih.gov/pubmed/18262393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2007.12.009
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