Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age

Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure) had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined whether such alterations are present from birth through adolescence. Methods: We used the Infinium HumanMethylation450K BeadC...

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Pubblicato in:Environ Health Perspect
Autori principali: Lee, Ken W.K., Richmond, Rebecca, Hu, Pingzhao, French, Leon, Shin, Jean, Bourdon, Celine, Reischl, Eva, Waldenberger, Melanie, Zeilinger, Sonja, Gaunt, Tom, McArdle, Wendy, Ring, Susan, Woodward, Geoff, Bouchard, Luigi, Gaudet, Daniel, Smith, George Davey, Relton, Caroline, Paus, Tomas, Pausova, Zdenka
Natura: Artigo
Lingua:Inglês
Pubblicazione: NLM-Export 2014
Soggetti:
Children's Health
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314251/
https://ncbi.nlm.nih.gov/pubmed/25325234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408614
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