Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age

Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure) had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined whether such alterations are present from birth through adolescence. Methods: We used the Infinium HumanMethylation450K BeadC...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Lee, Ken W.K., Richmond, Rebecca, Hu, Pingzhao, French, Leon, Shin, Jean, Bourdon, Celine, Reischl, Eva, Waldenberger, Melanie, Zeilinger, Sonja, Gaunt, Tom, McArdle, Wendy, Ring, Susan, Woodward, Geoff, Bouchard, Luigi, Gaudet, Daniel, Smith, George Davey, Relton, Caroline, Paus, Tomas, Pausova, Zdenka
Formato: Artigo
Idioma:Inglês
Publicado em: NLM-Export 2014
Assuntos:
Children's Health
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314251/
https://ncbi.nlm.nih.gov/pubmed/25325234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408614
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