Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism

Nutritional imbalance is emerging as a causative factor of hearing loss. Epidemiologic studies have linked hearing loss to elevated plasma total homocysteine (tHcy) and folate deficiency, and have shown that folate supplementation lowers tHcy levels potentially ameliorating age-related hearing loss....

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Udgivet i:FASEB J
Main Authors: Martínez-Vega, Raquel, Garrido, Francisco, Partearroyo, Teresa, Cediel, Rafael, Zeisel, Steven H., Martínez-Álvarez, Concepción, Varela-Moreiras, Gregorio, Varela-Nieto, Isabel, Pajares, María A.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2015
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314232/
https://ncbi.nlm.nih.gov/pubmed/25384423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-259283
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