Biphasic modulation by mGlu(5) receptors of TRPV1-mediated intracellular calcium elevation in sensory neurons contributes to heat sensitivity

BACKGROUND AND PURPOSE: Elevation of glutamate, an excitatory amino acid, during inflammation and injury plays a crucial role in the reception and transmission of sensory information via ionotropic and metabotropic receptors. This study aimed to investigate the mechanisms underlying the biphasic eff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Masuoka, T, Nakamura, T, Kudo, M, Yoshida, J, Takaoka, Y, Kato, N, Ishibashi, T, Imaizumi, N, Nishio, M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314192/
https://ncbi.nlm.nih.gov/pubmed/25297838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12962
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