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Biphasic modulation by mGlu(5) receptors of TRPV1-mediated intracellular calcium elevation in sensory neurons contributes to heat sensitivity
BACKGROUND AND PURPOSE: Elevation of glutamate, an excitatory amino acid, during inflammation and injury plays a crucial role in the reception and transmission of sensory information via ionotropic and metabotropic receptors. This study aimed to investigate the mechanisms underlying the biphasic eff...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4314192/ https://ncbi.nlm.nih.gov/pubmed/25297838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12962 |
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