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Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior

PURPOSE: To validate whether repeated magnetic resonance (MR) imaging–guided focused ultrasound treatments targeted to the hippocampus, a brain structure relevant for Alzheimer disease (AD), could modulate pathologic abnormalities, plasticity, and behavior in a mouse model. MATERIALS AND METHODS: Al...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Radiology
Κύριοι συγγραφείς: Burgess, Alison, Dubey, Sonam, Yeung, Sharon, Hough, Olivia, Eterman, Naomi, Aubert, Isabelle, Hynynen, Kullervo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Radiological Society of North America 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314115/
https://ncbi.nlm.nih.gov/pubmed/25222068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.14140245
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