Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control

Maintaining mitochondrial function is essential for neuronal survival and offers protection against neurodegeneration. Ubiquitin-mediated, proteasome-dependent protein degradation in the form of outer mitochondrial membrane associated degradation (OMMAD) was shown to play roles in maintenance of mit...

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Publicat a:Front Cell Neurosci
Autors principals: Fang, Lei, Hemion, Charles, Pinho Ferreira Bento, Ana C., Bippes, Claudia C., Flammer, Josef, Neutzner, Albert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313695/
https://ncbi.nlm.nih.gov/pubmed/25698929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00016
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