Ca(2+) cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells

Background: In animal models of heart failure (HF), heart rate decreases due to an increase in intrinsic cycle length (CL) of the sinoatrial node (SAN). Pacemaker activity of SAN cells is complex and modulated by the membrane clock, i.e., the ensemble of voltage gated ion channels and electrogenic p...

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Bibliografski detalji
Izdano u:Front Physiol
Glavni autori: Verkerk, Arie O., van Borren, Marcel M. G. J., van Ginneken, Antoni C. G., Wilders, Ronald
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Physiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313601/
https://ncbi.nlm.nih.gov/pubmed/25698973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00018
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