Ca(2+) cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells

Background: In animal models of heart failure (HF), heart rate decreases due to an increase in intrinsic cycle length (CL) of the sinoatrial node (SAN). Pacemaker activity of SAN cells is complex and modulated by the membrane clock, i.e., the ensemble of voltage gated ion channels and electrogenic p...

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Vydáno v:Front Physiol
Hlavní autoři: Verkerk, Arie O., van Borren, Marcel M. G. J., van Ginneken, Antoni C. G., Wilders, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313601/
https://ncbi.nlm.nih.gov/pubmed/25698973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00018
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