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A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent.

Replication of human immunodeficiency virus type 1 (HIV-1) is dependent on the viral Rev protein. This protein acts in concert with the cis-acting rev-responsive element present in intron-containing RNAs to facilitate nuclear export of these RNAs. Here we show that a cis-acting 219-nucleotide sequen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bray, M, Prasad, S, Dubay, J W, Hunter, E, Jeang, K T, Rekosh, D, Hammarskjöld, M L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1256
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