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A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent.

Replication of human immunodeficiency virus type 1 (HIV-1) is dependent on the viral Rev protein. This protein acts in concert with the cis-acting rev-responsive element present in intron-containing RNAs to facilitate nuclear export of these RNAs. Here we show that a cis-acting 219-nucleotide sequen...

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Autores principales: Bray, M, Prasad, S, Dubay, J W, Hunter, E, Jeang, K T, Rekosh, D, Hammarskjöld, M L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC43136/
https://ncbi.nlm.nih.gov/pubmed/8108397
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