טוען...
Overexpression of adenylyl cyclase type 5 (AC5) confers a proarrhythmic substrate to the heart
Inhibition of β-adrenergic receptor (β-AR) signaling is one of the most common therapeutic approaches for patients with arrhythmias. Adenylyl cyclase (AC) is the key enzyme responsible for transducing β-AR stimulation to increases in cAMP. The two major AC isoforms in the heart are types 5 and 6. Th...
שמור ב:
| הוצא לאור ב: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Physiological Society
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312946/ https://ncbi.nlm.nih.gov/pubmed/25485900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00630.2014 |
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