Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytes

Egress of malaria parasites from the host cell requires the concerted rupture of its enveloping membranes. Hence, we investigated the role of the plasmodial perforin-like protein PPLP2 in the egress of Plasmodium falciparum from erythrocytes. PPLP2 is expressed in blood stage schizonts and mature ga...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Wirth, Christine C, Glushakova, Svetlana, Scheuermayer, Matthias, Repnik, Urska, Garg, Swati, Schaack, Dominik, Kachman, Marika M, Weißbach, Tim, Zimmerberg, Joshua, Dandekar, Thomas, Griffiths, Gareth, Chitnis, Chetan E, Singh, Shailja, Fischer, Rainer, Pradel, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Special Issue on Malaria
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312913/
https://ncbi.nlm.nih.gov/pubmed/24602217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12288
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