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Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation
Taste sensation on the anterior tongue requires chorda tympani nerve function and connections with continuously renewing taste receptor cells. However, it is unclear which signaling pathways regulate the receptor cells to maintain chorda tympani sensation. Hedgehog (HH) signaling controls cell proli...
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| Publicado no: | J Neurophysiol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312875/ https://ncbi.nlm.nih.gov/pubmed/25392175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00822.2014 |
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