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The impact of FANCD2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines

Formaldehyde (FA), a major industrial chemical and ubiquitous environmental pollutant, has recently been classified by the International Agency for Research on Cancer as a human leukemogen. The major mode of action of FA is thought to be the formation of DNA-protein crosslinks (DPCs). Repair of DPCs...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Ren, Xuefeng, Ji, Zhiying, McHale, Cliona M., Yuh, Jessica, Bersonda, Jessica, Tang, Maycky, Smith, Martyn T., Zhang, Luoping
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312773/
https://ncbi.nlm.nih.gov/pubmed/22872141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-012-0911-6
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