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Isolation, primary structure, and synthesis of α-endorphin and γ-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity

The isolation and primary structure of two peptides with morphinomimetic activity, obtained from an extract of porcine hypothalamus-neurohypophysis, are described. The amino acid sequence of the two peptides, named α-endorphin and γ-endorphin, was determined by mass spectrometry and densyl-Edman met...

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Detalhes bibliográficos
Main Authors: Ling, Nicholas, Burgus, Roger, Guillemin, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431275/
https://ncbi.nlm.nih.gov/pubmed/1069261
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