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Computer aided screening of potent inhibitor compounds against inhibitor resistant TEM β-lactamase mutants from traditional Chinese medicine

Inhibitor-resistant TEM (IRT) type β-lactamase mutation is largely known. Therefore, it is of interest to identify new yet improved leads against IRT from traditional Chinese medicine. Hence, we screened more than 10,000 compounds from Chinese medicine (tcm@taiwan database) with mutant molecular IRT...

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Detalhes bibliográficos
Publicado no:Bioinformation
Main Authors: Zhu, Qifeng, Yin, Yanxia, Liu, Hanjie, Tian, Jinhong
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312368/
https://ncbi.nlm.nih.gov/pubmed/25670878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010750
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